Cleveland Daily Banner: ClinSearch

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Printed in the Cleveland Daily Banner- Wednesday, July 27, 2016

By WILLIAM WRIGHT, Lifestyle Editor

ClinSearch: Free Medical Treatment for Specific Health Disorders

Dr. Richard A. Krause, the medical director of ClinSearch, says if anyone is interested in getting the latest medical treatment not currently available to the public, his multi-specialty research facility is able to provide certain treatments at no cost (and with financial compensation), to qualified participants while furnishing them with safe, quality care.

Currently, Krause and his team of clinical research specialists are seeking individuals with irritable bowel syndrome and treating people suffering with NASH (nonalcoholic steatohepatitis) to decrease the risk of cirrhosis of the liver.  Krause said theirs is “a new treatment, and is very exciting.”

“We have a new treatment for GERD (gastroesophageal reflux disease), which is heartburn or acid reflux,” he added.  “It’s for people having heartburn more than twice a week.  We also have a new acne study for kids and adults, which we’re very exited about.”

ClinSearch is also treating, at no cost, individuals suffering from gastroparesis, which Krause describes as “poor emptying of the stomach,” as well as people dealing with constipation due to pain medications.

“We’re also working on what we call monoclonal antibodies, which is much more advanced treatment for certain diseases, particularly eczema,” Krause said.  “We’re doing an IV treatment for migraine headaches that we hope is going to prevent 75 percent of migraine headaches over a year.  One infusion will equal 75 percent improvement  over 3 to 6 months.  It’s amazing!  We’ll also be doing a cholesterol/triglyceride study and an irritable bowel/constipation study.  Those are some of our goals at the beginning of the year.  We welcome volunteers from Bradley county and other counties to call and apply for these programs.  There is no cost, and we reimburse people for their time and travel.”

Christy Sweet, clinical research manager, worked for eight years as a nurse supervisor in geriatrics.  Her research experience includes weight loss, IBS, constipation and a disorder that affects the digestive system called gastroparesis.  As a lead coordinator on a phase 1 Alzheimer’s vaccine trial, Sweet was one of the first research nurses to administer the vaccine in the United States.

According to Sweet, ClinSearch has seen some amazing results and progress that has helped its research participants live happier, healthier lives.  “It’s wonderful to see the results of these studies,” she said.  “We’re excited about all of our research, and how it is improving health conditions for so many people.”

Sweet said their weight loss study is also amazing as research participants are coming back after three months, stepping on the scales and being surprised at the weight loss.

Krause, who is board certified in internal medicine and gastroenterology, retired in 2006 to concentrate on medical research.  He has been chief of medicine and chief of gastroenterology as well as having served on the Parkridge Medical Center board.

According to Krause, ClinSearch has several participants from the Cleveland area, but he is interested in enrolling more.  Compensation for the research studies varies and is based on the time needed for each trial.  The research is voluntary, and patients can withdraw from the studies at any time.

“It’s a way for people to get new treatment that’s not available at this time,” he said.  “It’s for those who are not responding to treatment or can’t afford their treatments.  Anyone can get into a study once they meet the criteria.  What’s exciting about what we’re doing is that we’re working on some diseases for which there is no treatment.  For example, there is no treatment for Celiac Disease except for a very difficult diet.  We are studying three different ways to treat this gluten problem.  There are no good treatments for diabetics with poor emptying of the stomach.  We just finished studying a new treatment that seems to be very effective, and we should be doing additional studies very soon.  Patients that are constipated due to pain medication may improve on our new therapy.”

 Krause said he went into research in the early 1990’s after he realized insurance was controlling which doctors a patient could go to and which tests they would approve.

“If patients were not responding to current therapy, we had nothing to offer them,” he said.  “Now we do – IF patients are willing to volunteer to try new treatments.  Our patients are compensated for time and travel and receive study-related treatment, lab work, EKG and procedures at no cost to the patient or their insurance.  We are always looking for volunteers to help in our irritable bowel studies and chronic constipation.”

According to Krause, who spent three years at Emory University and Grady Memorial Hospital in internal medicine, one year at Yale University for a fellowship in gastroenterology and an additional year at the University of Massachusetts for gastroenterology, his experienced staff enrolls new patients through physician referrals, database notification and community awareness events.

The physician said research necessary to improve human health and medical care depends on the participation of human subjects.  Therefore it is only reasonable to financially compensate patients who otherwise could not afford to participate.  Many of Krause’s patients recommend ClinSearch as a means of helping the community, themselves and the medical profession to devise better medical treatment because of the research done by ClinSearch.

“Our current facility database has a patient population of more than 10,000 and growing,” Krause said.  “We have a motivated, hard-working staff with an excellent track record of producing quality data in a timely fashion, with 24-hour emergency contact by phone.”

Krause said he wanted to reach out to anyone 18 and older (some studies accept those in their 70’s and 80’s) in areas like Bradley County, Polk, Meigs, McMinn and other surrounding counties for greater participation in these clinical studies. ClinSearch is an independent Clinical Research Center.

For further information, call (423) 698-4584 or visit