Topic: Insider

ClinSearch to Partner with the Sjögren’s Syndrome Foundation

Posted on October 16, 2017

We are excited to announce our partnership with the Sjögren’s Syndrome Foundation and to get the word out about our ongoing clinical research study of Sjögren’s Syndrome. Below is a letter the foundation has sent out on our behalf:

October 2017

Dear Sjögren’s Patient:

Each day research and clinical trials are being conducted to unveil new medications, therapies and diagnostic tools for Sjögren’s syndrome and its symptoms. Listed below is information about a Sjögren’s clinical research study being held in the greater Chattanooga area. Your participation in this study could help patients worldwide and I hope you will consider learning more.

This new Sjögren’s clinical study looking for men and women, age 18-75 with Sjögren’s syndrome. Qualified participants will receive study-related medication and medical exams at no cost, and compensation for travel costs.

 

For more information and to see if you may be eligible to participate, contact:

 ClinSearch

6035 Shallowford Rd. #109

Chattanooga, TN 37421

www.clinsearch-us.com

 

Call: (423) 698-4584 or email info@clinsearch-us.com

If you have questions regarding the project, please contact the number listed above and not the Foundation Office.

 On behalf of the millions of Sjögren’s sufferers in this country, I thank you for taking time to learn more about this study.

 

Sincerely,

Steven Taylor

Chief Executive Officer

 

To find out more about the Sjögren’s Syndrome Foundation, please visit their website at: http://www.sjogrens.org/

To learn more about our clinical research study examining the safety and effectiveness of an investigational medication for individuals with Sjögren’s syndrome, click here.

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October Newsletter 2017

Posted on October 16, 2017

Read our latest blog post to learn about
Crohn’s Disease, Ulcerative Colitis and You.

Featured Studies

Nonalcoholic Steatohepatitis or Fatty Liver?
ClinSearch is currently enrolling for a clinical research study for the treatment of cirrhosis from NASH. Visit our website to find out more about this study.

 

 

 

Acne
ClinSearch is enrolling volunteers who experience acne. If you are at least 9 years old, you may qualify for a clinical research trail. Visit us here to learn more.

 

 

 

Eczema (Atopic Dermatitis)
Do you or a loved one suffer from eczema, also known at atopic dermatitis? ClinSearch is enrolling volunteers in a clinical research study for individuals with eczema. Learn more here.

 

 

 

Other Studies

 

Fibromyalgia
We are studying a new treatment for Fibromyalgia. Patients must be 18-79 with a confirmed diagnosis of fibromyalgia. Other qualifications may apply.
There is no cost for this study and you may be compensated for your time and travel. Visit our website to learn more and to see if you qualify.

 

 

 

Ulcerative Colitis
Do you experience the discomfort of ulcerative colitis? If so, you may qualify for a clinical research study at ClinSearch. Visit our website to learn more about this enrolling study.

 

 

 

Gastroparesis
Gastroparesis is a condition in which your stomach cannot empty itself of food in a normal fashion. If you are interested in participating in one of our Gastroparesis studies, visit us here.

 

 

 

Crohn’s Disease
There are 1.4 million Americans with Crohn’s disease. ClinSearch is conducting new research on the treatment of this disease.
Check out Dr. Krause’s recent blog post to learn more about this condition and the studies we are doing here at ClinSearch.

 

 

Sjorgren’s Syndrome
Dry mouth and eyes from Sjogren’s syndrome? If so, you may qualify for a clinical research study at ClinSearch examining an investigational medication for individuals with Sjogren’s syndrome. Learn about the study here.

 

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Crohn’s Disease, Ulcerative Colitis and You

Posted on September 27, 2017

Crohn’s Disease and Ulcerative Colitis are both chronic inflammatory diseases of the GI tract.

Ulcerative Colitis involves only the colon and Crohn’s can involve any part of the GI tract (from the mouth to anus).

Both occur most frequently in men and women between the ages of 15-35.

Symptoms vary but can include:

  • Diarrhea
  • Rectal bleeding
  • Abdominal pain
  • Weight loss
  • Liver problems
  • Kidney problems

Cause of either is unknown, but may be a combination of genetics, immune system or environment. There appears to be an over-reaction of the immune system attacking the gut.

There is no cure, but we can control symptoms by suppressing the immune system using:

  • Steroids
  • Anti TNF drugs
  • Vedolizumab
  • 6MP

ClinSearch has several new studies to treat Crohn’s or Ulcerative Colitis not responding to current treatment.

For more information on our Crohn’s study, please click here.

For more information on our Ulcerative Colitis study, please click here.

Contact us at 423-698-4584 or go to our website at www.clinsearch-us.com

 

 

September Newsletter 2017

Posted on September 5, 2017

Featured Studies

 

Ulcerative Colitis
 

Do you experience the discomfort of ulcerative colitis? If so, you may qualify for a clinical research study at ClinSearch. Visit our website to learn more about this enrolling study.

 

IBS-C or IBS-D
Do you suffer with the symptoms of irritable bowel syndrome? Volunteers with either IBS-C or IBS-D are needed for current studies at our site. Visit us for more information about IBS-C and IBS-D.

 
 

Gastroparesis
Gastroparesis is a condition in which your stomach cannot empty itself of food in a normal fashion. If you are interested in participating in one of our Gastroparesis studies, visit us here.

 

 

Other Studies

 

Fibromyalgia
We are studying a new treatment for Fibromyalgia. Patients must be 18-79 with a confirmed diagnosis of fibromyalgia. Other qualifications may apply.
There is no cost for this study and you may be compensated for your time and travel. Visit our website to learn more and to see if you qualify.

 

Crohn’s Disease
There are 1.4 million Americans with Crohn’s disease. ClinSearch is conducting new research on the treatment of this disease.
Check out Dr. Krause’s recent blog post to learn more about this condition and the studies we are doing here at ClinSearch.

 
 

Nonalcoholic Steatohepatitis or Fatty Liver?
ClinSearch is currently enrolling for a clinical research study for the treatment of cirrhosis from NASH. Visit our website to find out more about this study.

 

 

Type 2 Diabetes and High Triglycerides
If you have type 2 diabetes and high triglycerides you may qualify for a study at ClinSearch.
Find out more here.

 

 

Type 1 and Type 2 Diabetes
ClinSearch will be enrolling studies for individuals with either Type 1 or Type 2 diabetes. If you experience either of these conditions you may qualify for our clinical research studies. To learn more visit our website here.

 

 

Sjorgren’s Syndrome
Dry mouth and eyes from Sjogren’s syndrome? If so, you may qualify for a clinical research study at ClinSearch examining an investigational medication for individuals with Sjogren’s syndrome. Learn about the study here.

 

 

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Join ClinSearch at the Hamilton County Minority Health Fair on Saturday 8/19

Posted on August 16, 2017

Closing the Health Gap in Our Community:

Join ClinSearch at the 15th annual Hamilton County Minority Health Fair, Saturday, 8/19 from 9:00 AM until 2:00 PM at Eastgate town Center.

Participants can receive a variety of health screenings and health information. Attendees can also safely dispose of unused, or expired prescription medication.

See details @ www.sethc.org

View more here: https://youtu.be/d82MLnzKzC0

ClinSearch has provided our community with access to clinical research trials since 1992. We serve volunteers from the greater Chattanooga area, Cleveland, Dalton, Georgia and North-Eastern Alabama with access to clinical trials. While each individual trial varies, most offer study-related investigational drug and medical exams at no cost, and compensation for your time and travel.

ClinSearch is always looking for qualified volunteers. If you want to know more about new treatment options, give us a call (423) 698-4584 or request more information here.

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August Newsletter 2017

Posted on August 1, 2017

Acne Study

Is your acne getting in your way? ClinSearch is enrolling a study for individuals suffering from acne. Visit our website to learn more about this study: Link

 

Crohn’s Disease

There are 1.4 million Americans with Crohn’s disease. ClinSearch is conducting new research on the treatment of this disease.
Check out Dr. Krause’s latest blog post to learn more about this condition and the studies we are doing here at ClinSearch.

 

Type 2 Diabetes and High Triglycerides

If you have type 2 diabetes and high triglycerides you may qualify for a study at ClinSearch.
Find out more here.

 

 

Fibromyalgia

We are studying a new treatment for Fibromyalgia. Patients must be 18-79 with a confirmed diagnosis of fibromyalgia. Other qualifications may apply.
There is no cost for this study and you may be compensated for your time and travel. Visit our website to learn more and to see if you qualify.

 

Nonalcoholic Steatohepatitis or Fatty Liver?

Nonalcoholic steatohepatitis or NASH is liver inflammation caused by a buildup of fat in the liver. Dr. Krause has written about this topic to help individuals better understand this condition on his blog.
ClinSearch is currently enrolling for a clinical research study for the treatment of cirrhosis from NASH. Visit our website to find out more about this study.

 

  Atopic Dermatitis (Eczema)

Eczema is a condition that affects 2-10% of adults in the United States. ClinSearch is enrolling individuals who have eczema in a clinical research study. If you suffer from this condition and would like to participate, visit our website here to learn more about getting involved.  Additionally, if you are interested in learning about this condition you can read what Dr. Krause has to say here.

 

Migraines

Do you suffer from migraines? If the pain of migraine headaches is getting in your way, you may qualify for a clinical research study at ClinSearch.
Visit us online to learn more: link

 

 
 

Want to know more about participating in clinical research? Read more on our website.

 

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Crohn’s Disease

Posted on June 6, 2017

There are 1.4 million Americans with Crohn’s. This disease is usually diagnosed between the age 15-30. Additionally, 5-20% of individuals with Crohns have a family history of the disease.

Though the cause is unknown, we known that the symptoms are caused by a hyperactive immune system attacking the gut. Crohn’s may involve any part of the GI tract but usually the distal small bowel (ileum) and the colon.

Symptoms vary depending on the section of the gut involved, but usually include:

  • Diarrhea (with possible constipation)
  • Rectal bleeding if colon is involved
  • Weight loss
  • Fever
  • Abdominal pain
  • Fatigue
  • Loss of appetite

Complications include obstructions, fissures in the rectum, fistulas, cancer and perforation. Crohn’s may also involve areas outside the GI tract such as eyes, skin, kidney stones and joints. There is no current cure but patients may go into remission with medication.

There are several different treatments including:

  • 5 ASA (special aspirin)
  • Steroids
  • Immune modifiers (imuran, 6MP)
  • Biologics (Remicaid, Humira)

Surgery is a last resort since many patients have recurrent disease despite surgery. Most drugs suppress the immune system with increased risk of infection and cancer.

We are studying 2 new types of treatment:

  1. Triple antibiotics designed to kill MAP bacteria that may be the cause of Crohn’s in some patients.
  2. New type of oral treatments that will normalize the immune system rather than suppress it.

To see if you qualify for one of our studies, contact us at 423-698-4584.

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IBS – Irritable Bowel Syndrome

Posted on March 21, 2017

Do you or one of your friends have irritable bowel syndrome (IBS)? We may be able to help.

What is IBS?

  • IBS is a group of digestive symptoms including abdominal pain or discomfort improved by passing stool. Bowel irregularity (either diarrhea or constipation)
  • It is not life threatening and it does not progress into more serious diseases. However, it can definitely affect your qualify of life.

IBS is very common, affecting 25-45 million Americans, mostly women starting in the late teens. It is the second most common cause for missing work and is associated with a higher risk of gall bladder surgery and  hysterectomy.

There are three types of IBS:

  • IBS-Constipation
  • IBS-Diarrhea
  • IBS-Alternating constipation with diarrhea

What causes IBS? There are multiple possible causes of IBS including: 

  • Gut to brain communication defect
  • Hypersensitivity of the gut
  • Altered bacteria in the gut
  • Leaky gut
  • Serotonin problems
  • Post infectious IBS
  • Hormones and stress may be a factor, but not a cause

How to diagnose:

There is no specific test so some believe you must rule out other diseases (Crohn’s, Microscopic Colitis, Celiac, etc.). However, there is a blood test to determine if you have post infectious IBS.

How to Treat IBS: 

  • Avoid food that may trigger  your symptoms
  • Avoid caffeine
  • Add more fiber
  • Drink more water
  • Stop smoking
  • Exercise
  • Reduce stress
  • Watch for lactose intolerance or gluten intolerance

Medication: 

  • Anti-Spasmodic may help cramps
  • Anti-Diarrheal may help diarrhea
  • Low dose antidepressant for pain
  • Linzess for IBS-Constipation
  • Viberza for IBS-Diarrea
  • Xafaxan for IBS-Diarrhea
  • OTC IBgard for IBS-D
  • Enteragam OTC for IBS-Diarrhea
  • Probiotics

ClinSearch is alway doing studies for patients with IBS. To see if you qualify, call (423)698-584.

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NASH – Fatty Liver

Posted on March 21, 2017

Do you or a friend have NASH or Fatty Liver? We may be able to help.

What is NASH (non alcoholic steatohepatitis)?

  • Liver inflammation and damage caused by a build-up of fat in the liver (fatty liver) that in some people triggers inflammation (hepatitis) and damage (fibrosis that may lead to cirrhosis)
  • There is an increased risk of NASH in people with:
    • Obesity
    • Diabetes
    • Elevated cholesterol and triglycerides
    • High blood pressure
    • Family history

What are the symptoms? 

There are no symptoms at first. However, over time the liver disease may progress to fatigue, weight loss, weakness and right upper abdominal discomfort.

How to diagnose:

  • Ultrasound of the liver
  • CAT scan
  • MRI scan
  • Fibro scan
  • Blood test
  • Liver Biopsy

Complications of cirrhosis include:

  • Esophageal varices with bleeding
  • Encephalopathy (confusion even coma)
  • Ascites (fluid build-up in the abdomen)

How to treat:

  • Reduce Cholesterol
  • Lose weight
  • Control diabetes
  • Reduce alcohol
  • Exercise
  • Vitamin E

There is no approved medication to treat NASH but ClinSearch is studying new therapies.

To see if you qualify, call (423)698-4584.

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Eczema – Atopic Dermatitis

Posted on March 21, 2017

Do you or a friend have eczema? We may be able to help.

What is eczema?

  • Eczema is a common chronic inflammatory skin disease affecting 2-10% of adults in the U.S.
  • The skin is inflamed or irritated most commonly on the face, back of the elbows and knees, wrists, hands and feet.
  • Affected areas are very dry, thickened or scale. It may be crusty or oozing. It almost always itches.

What causes eczema?

  • The cause is unknown but may be related to an overactive response of the immune system resulting in defects in the skin barrier allowing loss of moisture and letting bacteria.
  • It is found in families with allergies or asthma.
  • The rash may be triggered by exposure to heat, cold, soap and the household products.
  • It may be triggered by respiratory infections and stress

How do you treat eczema?

There is not a cure but the goal is treatment of symptoms. Some treatments include:

  • Anti itch medication (antihistamine)
  • Anti itch creams ( hydrocortisone or calamine lotion)
  • Moisturize skin twice a day
  • Cool, wet compresses
  • Warm bath with uncooked oatmeal
  • Avoid or treat stress
  • Avoid hot showers, scratching, wool clothing, smoke and dust

Other options include phototherapy, oral steroids, elides and protonic (alter the immune system but may risk skin cancer).

What is new:
At ClinSearch we are studying new treatments for more severe eczema and a new treatment for severe itching.

To see if you qualify, contact us at (423)698-4584.

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